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KMID : 0438219780150030195
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Korea University Medical Journal
1978 Volume.15 No. 3 p.195 ~ p.204
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The Influence of Enzyme (Urokinase^(R)) and Liquefaction of Vireous on Absorption of Simulated Vitreous Hemorrhages
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Abstract
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This investigation was undertaken to study the mechanisms involved in the absorption of blood from the vitreous, and was divided into following experimental groups:
A) Eyes injected with 0.1cc whole blood (7 eyes)
B) Eyes injected with . icc hemolyzed blood (7 eyes)
C) Eyes injected with o. ice (12 N/o.1ml) urokinase solution after 0. lcc whole blood injection
(7 eyes).
D) Eyes injected with 6.1cc whole blood after 0.8cc vitreous aspiration (7 eyes).
E). Combined group of-C) and 1))-(´ eyes).
In each-experimental group,-simula. -vitreous hemorrhages were induced in rabbits by intravitreal
injection of 0 1"u6logous radioactive chromium (5´Cr) tagged blood through the pars: plans at, 12 o´clock position. Thereafter-. therates -of change of radioactivity of the eyes were measu´retwith´ ` a scintillation counter once a day for 10 days and their percentages were obtained.
The results obtained ´were as follows:
1) The average rate´ of removal of `whole blood group from the vitreous cavity for 50% of the injected radioactivity---to disappear was approximately 4/5 times those of homolyied group and combined group, -and 2,15´times´#last of-urokinase group, $15 times that of vitreous aspiration group, ´ -2) The- average- rate of removal of whole blood group from the vitreous´ cavity for 75% of the injected
-- radioactivity, to disappear was s40rozinmately -113 times that of `hemolyzed blood, andt times those of urokinase group. and combined group,.
t~ ´t lvas´ onclud t diffusio .o#´.blood el t4P;, h aiid alternation
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KEYWORD
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